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Gonadal steroidgenesis in girls starts with production of testosterone which is typically quickly converted to estradiol inside the ovaries.

In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs.Physical growth—height and weight—accelerates in the first half of puberty and is completed when an adult body has been developed.1 Follicle-stimulating hormone - FSH 2 Luteinizing hormone - LH 3 Progesterone 4 Estrogen 5 Hypothalamus 6 Pituitary gland 7 Ovary 8 Pregnancy - h CG (Human chorionic gonadotropin) 9 Testosterone 10 Testicle 11 Incentives 12 Prolactin - PRL Two of the most significant differences between puberty in girls and puberty in boys are the age at which it begins, and the major sex steroids involved, the testosterones and the estrogens.Although there is a wide range of normal ages, girls typically begin the process of puberty at age 10 or 11; boys at ages 11–12.Notable among the morphologic changes in size, shape, composition, and functioning of the pubertal body, is the development of secondary sex characteristics, the "filling in" of the child's body; from girl to woman, from boy to man.

Derived from the Latin puberatum (age of maturity), the word puberty describes the physical changes to sexual maturation, not the psychosocial and cultural maturation denoted by the term adolescent development in Western culture, wherein adolescence is the period of mental transition from childhood to adulthood, which overlaps much of the body's period of puberty.In general, girls who enter puberty late experience positive outcomes in adolescence and adulthood while girls who enter puberty early experience negative outcomes.Boys who have earlier pubertal timing generally have more positive outcomes in adulthood but more negative outcomes in adolescence, while the reverse is true for later pubertal timing.The male "growth spurt" also begins later, accelerates more slowly, and lasts longer before the epiphyses fuse.Although boys are on average 2 centimetres (0.8 in) shorter than girls before puberty begins, adult men are on average about 13 centimetres (5.1 in) taller than women.The researchers hypothesized that Neurokinin B might play a role in regulating the secretion of Kisspeptin, a compound responsible for triggering direct release of Gn RH as well as indirect release of LH and FSH.